Yucca Health vs Trimi: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and Trimi to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.3 vs 9.1), availability in all 50 states. That said, Trimi may be the better fit if you are looking for cash-pay users who want the cheapest tirzepatide from a us-licensed program.
Yucca Health scores 9.3/10 in our independent evaluation at $146/month, while Trimi scores 9.1/10 at $99/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | Trimi |
|---|---|---|
| Monthly Price | $146 | $99 |
| Rating | 9.3 / 10 | 9.1 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 47 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | US-licensed clinicians, telehealth consults, dose adjustments |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
Trimi: Detailed Look
Trimi
Compounded GLP-1 from $99 with US-licensed clinicians
Pros
- Tirzepatide at $125/month — lowest tirzepatide price among verified programs
- Semaglutide at $99/month matches the market floor
- US-licensed clinicians with dose-adjustment support
- Free shipping to your door
Cons
- New program with a short independent track record
- No brand-name (Wegovy/Zepbound) pathway
Cash-pay users who want the cheapest tirzepatide from a US-licensed program
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Trimi at $99/month. Semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track.
Yucca Health has the edge with a 9.3 rating.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while Trimi provides us-licensed clinicians, telehealth consults, dose adjustments.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than Trimi?
Yucca Health has a 9.3 rating while Trimi has a 9.1 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while Trimi is best for cash-pay users who want the cheapest tirzepatide from a us-licensed program.
How much does Yucca Health cost compared to Trimi?
Yucca Health starts at $146/month ($146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. klarna/affirm/afterpay available.), while Trimi starts at $99/month (semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track).
Do Yucca Health and Trimi accept insurance?
Yucca Health does not accept insurance. Trimi does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs Trimi?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Yucca Health or Trimi at any time?
Yucca Health may have cancellation restrictions. Trimi also allows cancel anytime.
Are Yucca Health and Trimi available in my state?
Yucca Health is available in all 50 states. Trimi is available in 47 states.
Not sure Yucca Health or Trimi is right for you?
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