Yucca Health vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend TMates
Between these two providers, TMates is our pick for most users. It offers a higher overall rating (7.8 vs 7.7), insurance acceptance. That said, Yucca Health may be the better fit if you are looking for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost.
Side-by-Side Comparison
| Feature | Yucca Health | TMates |
|---|---|---|
| Monthly Price | $146 | $199 |
| Rating | 7.7 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | 45 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed providers, asynchronous review | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Yucca Health: Detailed Look
Yucca Health
Competitive GLP-1 pricing with fast 2-day shipping and flexible payment
Pros
- Competitive pricing on 6-month plans
- Fast UPS 2-Day Air shipping included
- Flexible payment via Affirm, Klarna, and Afterpay
- No live doctor visit required — fully asynchronous review
Cons
- Pricing only revealed after completing intake form
- Does not provide HSA/FSA receipts for reimbursement
Price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo semaglutide on 6-month plan, $258/mo tirzepatide.
TMates has the edge with a 7.8 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Yucca Health offers licensed providers, asynchronous review, while TMates provides licensed providers, sms coaching, digital check-ins.
TMates at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than TMates?
Yucca Health has a 7.7 rating while TMates has a 7.8 rating. The better choice depends on your priorities — Yucca Health is best for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does Yucca Health cost compared to TMates?
Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide), while TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide).
Do Yucca Health and TMates accept insurance?
Yucca Health does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does Yucca Health offer vs TMates?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel Yucca Health or TMates at any time?
Yucca Health may have cancellation restrictions. TMates also allows cancel anytime.
Are Yucca Health and TMates available in my state?
Yucca Health is available in 45 states. TMates is available in 45 states.