Yucca Health vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 7.8), more affordable pricing, availability in all 50 states. That said, TMates may be the better fit if you are looking for users with insurance who want a coached glp-1 program with multiple medication options.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while TMates scores 7.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | TMates |
|---|---|---|
| Monthly Price | $146 | $199 |
| Rating | 9.2 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo semaglutide on 6-month plan, $258/mo tirzepatide. Klarna/Affirm/Afterpay available..
Yucca Health has the edge with a 9.2 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while TMates provides licensed providers, sms coaching, digital check-ins.
TMates at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than TMates?
Yucca Health has a 9.2 rating while TMates has a 7.8 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does Yucca Health cost compared to TMates?
Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide. klarna/affirm/afterpay available.), while TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide).
Do Yucca Health and TMates accept insurance?
Yucca Health does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does Yucca Health offer vs TMates?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel Yucca Health or TMates at any time?
Yucca Health may have cancellation restrictions. TMates also allows cancel anytime.
Are Yucca Health and TMates available in my state?
Yucca Health is available in all 50 states. TMates is available in 45 states.