Yucca Health vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Sesame Care
Between these two providers, Sesame Care is our pick for most users. It offers a higher overall rating (7.8 vs 7.7), more affordable pricing, availability in all 50 states, insurance acceptance, both brand-name and compounded medication options. That said, Yucca Health may be the better fit if you are looking for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost.
Side-by-Side Comparison
| Feature | Yucca Health | Sesame Care |
|---|---|---|
| Monthly Price | $146 | $25 |
| Rating | 7.7 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed providers, asynchronous review | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Yucca Health: Detailed Look
Yucca Health
Competitive GLP-1 pricing with fast 2-day shipping and flexible payment
Pros
- Competitive pricing on 6-month plans
- Fast UPS 2-Day Air shipping included
- Flexible payment via Affirm, Klarna, and Afterpay
- No live doctor visit required — fully asynchronous review
Cons
- Pricing only revealed after completing intake form
- Does not provide HSA/FSA receipts for reimbursement
Price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users who want cheap doctor visits and already have insurance to cover brand-name medications
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Sesame Care at $25/month. $25-75 per visit; medication costs separate.
Sesame Care has the edge with a 7.8 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: Yucca Health offers licensed providers, asynchronous review, while Sesame Care provides licensed physicians, per-visit model.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than Sesame Care?
Yucca Health has a 7.7 rating while Sesame Care has a 7.8 rating. The better choice depends on your priorities — Yucca Health is best for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost, while Sesame Care is best for users who want cheap doctor visits and already have insurance to cover brand-name medications.
How much does Yucca Health cost compared to Sesame Care?
Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide), while Sesame Care starts at $25/month ($25-75 per visit; medication costs separate).
Do Yucca Health and Sesame Care accept insurance?
Yucca Health does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does Yucca Health offer vs Sesame Care?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel Yucca Health or Sesame Care at any time?
Yucca Health may have cancellation restrictions. Sesame Care also allows cancel anytime.
Are Yucca Health and Sesame Care available in my state?
Yucca Health is available in 45 states. Sesame Care is available in all 50 states.