Yucca Health vs Hone Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and Hone Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.3 vs 6.3), more affordable pricing, availability in all 50 states. That said, Hone Health may be the better fit if you are looking for users who want a full-service health platform covering weight loss plus hormones and labs.
Yucca Health scores 9.3/10 in our independent evaluation at $146/month, while Hone Health scores 6.3/10 at $160/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | Hone Health |
|---|---|---|
| Monthly Price | $146 | $160 |
| Rating | 9.3 / 10 | 6.3 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 44 states |
| Consultation Fee | Free | $65 initial lab kit |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | Licensed physicians, lab testing, ongoing monitoring |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
Hone Health: Detailed Look
Hone Health
Full-service telehealth with GLP-1s, hormone therapy, and lab testing
Pros
- Full clinical platform — weight loss, hormones, longevity, and labs
- Advanced lab diagnostics included to guide treatment
- Private telehealth consults with licensed physicians
- Medications shipped directly to your door
Cons
- Requires separate membership fee ($25-149/mo) on top of medication
- Does not offer semaglutide — only liraglutide and tirzepatide
Users who want a full-service health platform covering weight loss plus hormones and labs
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. Klarna/Affirm/Afterpay available..
Yucca Health has the edge with a 9.3 rating.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while Hone Health provides licensed physicians, lab testing, ongoing monitoring.
Hone Health at $160/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than Hone Health?
Yucca Health has a 9.3 rating while Hone Health has a 6.3 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while Hone Health is best for users who want a full-service health platform covering weight loss plus hormones and labs.
How much does Yucca Health cost compared to Hone Health?
Yucca Health starts at $146/month ($146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. klarna/affirm/afterpay available.), while Hone Health starts at $160/month ($160/mo liraglutide, $349-499/mo tirzepatide + membership fee).
Do Yucca Health and Hone Health accept insurance?
Yucca Health does not accept insurance. Hone Health does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs Hone Health?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. Hone Health offers Compounded Liraglutide, Compounded Tirzepatide.
Can I cancel Yucca Health or Hone Health at any time?
Yucca Health may have cancellation restrictions. Hone Health also allows cancel anytime.
Are Yucca Health and Hone Health available in my state?
Yucca Health is available in all 50 states. Hone Health is available in 44 states.
Not sure Yucca Health or Hone Health is right for you?
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