Yucca Health vs AgelessRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and AgelessRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend AgelessRx
Between these two providers, AgelessRx is our pick for most users. It offers a higher overall rating (8 vs 7.7), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, Yucca Health may be the better fit if you are looking for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost.
Side-by-Side Comparison
| Feature | Yucca Health | AgelessRx |
|---|---|---|
| Monthly Price | $146 | $139 |
| Rating | 7.7 / 10 | 8 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed providers, asynchronous review | Licensed providers, ongoing clinical support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Yucca Health: Detailed Look
Yucca Health
Competitive GLP-1 pricing with fast 2-day shipping and flexible payment
Pros
- Competitive pricing on 6-month plans
- Fast UPS 2-Day Air shipping included
- Flexible payment via Affirm, Klarna, and Afterpay
- No live doctor visit required — fully asynchronous review
Cons
- Pricing only revealed after completing intake form
- Does not provide HSA/FSA receipts for reimbursement
Price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost
AgelessRx: Detailed Look
AgelessRx
Longevity-focused telehealth with compounded GLP-1s and oral drops
Pros
- Longevity platform — also offers NAD+, rapamycin, metformin
- Oral GLP-1 drops available for needle-free option
- Free consultations with no separate provider fees
- Available in all 50 states with HSA/FSA accepted
Cons
- Cold-shipped injectables may not be available in Alaska/Hawaii
- Compounded medications are not FDA-reviewed for safety
Longevity-minded users who want GLP-1 alongside anti-aging treatments
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with AgelessRx at $139/month. $139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide.
AgelessRx has the edge with a 8 rating.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: Yucca Health offers licensed providers, asynchronous review, while AgelessRx provides licensed providers, ongoing clinical support.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than AgelessRx?
Yucca Health has a 7.7 rating while AgelessRx has a 8 rating. The better choice depends on your priorities — Yucca Health is best for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost, while AgelessRx is best for longevity-minded users who want glp-1 alongside anti-aging treatments.
How much does Yucca Health cost compared to AgelessRx?
Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide), while AgelessRx starts at $139/month ($139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide).
Do Yucca Health and AgelessRx accept insurance?
Yucca Health does not accept insurance. AgelessRx does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs AgelessRx?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. AgelessRx offers Compounded Semaglutide, Compounded Tirzepatide, Compounded Liraglutide, Oral GLP-1 Drops, Wegovy, Zepbound.
Can I cancel Yucca Health or AgelessRx at any time?
Yucca Health may have cancellation restrictions. AgelessRx also allows cancel anytime.
Are Yucca Health and AgelessRx available in my state?
Yucca Health is available in 45 states. AgelessRx is available in all 50 states.