Yucca Health vs AgelessRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and AgelessRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 6.1). That said, AgelessRx may be the better fit if you are looking for longevity-minded users who want glp-1 alongside anti-aging treatments.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while AgelessRx scores 6.1/10 at $139/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | AgelessRx |
|---|---|---|
| Monthly Price | $146 | $139 |
| Rating | 9.2 / 10 | 6.1 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | Licensed providers, ongoing clinical support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
AgelessRx: Detailed Look
AgelessRx
Longevity-focused telehealth with compounded GLP-1s and oral drops
Pros
- Longevity platform — also offers NAD+, rapamycin, metformin
- Oral GLP-1 drops available for needle-free option
- Free consultations with no separate provider fees
- Available in all 50 states with HSA/FSA accepted
Cons
- Cold-shipped injectables may not be available in Alaska/Hawaii
- Compounded medications are not FDA-reviewed for safety
Longevity-minded users who want GLP-1 alongside anti-aging treatments
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with AgelessRx at $139/month. $139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide.
Yucca Health has the edge with a 9.2 rating.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while AgelessRx provides licensed providers, ongoing clinical support.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than AgelessRx?
Yucca Health has a 9.2 rating while AgelessRx has a 6.1 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while AgelessRx is best for longevity-minded users who want glp-1 alongside anti-aging treatments.
How much does Yucca Health cost compared to AgelessRx?
Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide. klarna/affirm/afterpay available.), while AgelessRx starts at $139/month ($139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide).
Do Yucca Health and AgelessRx accept insurance?
Yucca Health does not accept insurance. AgelessRx does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs AgelessRx?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. AgelessRx offers Compounded Semaglutide, Compounded Tirzepatide, Compounded Liraglutide, Oral GLP-1 Drops, Wegovy, Zepbound.
Can I cancel Yucca Health or AgelessRx at any time?
Yucca Health may have cancellation restrictions. AgelessRx also allows cancel anytime.
Are Yucca Health and AgelessRx available in my state?
Yucca Health is available in all 50 states. AgelessRx is available in all 50 states.