SkinnyRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of SkinnyRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.
SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | SkinnyRx | Sesame Care |
|---|---|---|
| Monthly Price | $199 | $225 |
| Rating | 9.1 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 48 states | All 50 states |
| Consultation Fee | Included | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, 24-48hr prescription review | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
SkinnyRx: Detailed Look
SkinnyRx
Fastest-growing GLP-1 provider — oral, sublingual, and injectable options with Affirm financing
Pros
- Three delivery forms: injectable, sublingual, and oral tablets
- Free overnight shipping from FDA-regulated U.S. pharmacies
- Month-to-month billing with no contracts
- 4.8/5 Trustpilot rating from thousands of verified reviews
Cons
- Cash-pay only — no insurance billing
- Compounded medications only — no brand-name options
Users who want multiple delivery forms (oral, sublingual, injectable) for their GLP-1
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users with insurance who want cheap doctor visits — medication costs are separate and not included
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with SkinnyRx at $199/month. $199/mo semaglutide, up to $349/mo for tirzepatide.
SkinnyRx has the edge with a 9.1 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: SkinnyRx offers licensed u.s. physicians, 24-48hr prescription review, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is SkinnyRx better than Sesame Care?
SkinnyRx has a 9.1 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — SkinnyRx is best for users who want multiple delivery forms (oral, sublingual, injectable) for their glp-1, while Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included.
How much does SkinnyRx cost compared to Sesame Care?
SkinnyRx starts at $199/month ($199/mo semaglutide, up to $349/mo for tirzepatide), while Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.).
Do SkinnyRx and Sesame Care accept insurance?
SkinnyRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does SkinnyRx offer vs Sesame Care?
SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel SkinnyRx or Sesame Care at any time?
SkinnyRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are SkinnyRx and Sesame Care available in my state?
SkinnyRx is available in 48 states. Sesame Care is available in all 50 states.