ShedRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.
ShedRx scores 8.8/10 in our independent evaluation at $199/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Sesame Care |
|---|---|---|
| Monthly Price | $199 | $225 |
| Rating | 8.8 / 10 | 7.2 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 10% weight loss guarantee within 9 months or full refund
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- Price increases at higher doses (up to $299/mo)
- Mixed customer service reviews — communication speed can lag
Users who want multiple medication delivery forms and a money-back weight loss guarantee
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users with insurance who want cheap doctor visits — medication costs are separate and not included
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with ShedRx at $199/month. $199/mo semaglutide starting dose, up to $299/mo at higher doses. Brand pathway $99/mo + pharmacy cost..
ShedRx has the edge with a 8.8 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Sesame Care?
ShedRx has a 8.8 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included.
How much does ShedRx cost compared to Sesame Care?
ShedRx starts at $199/month ($199/mo semaglutide starting dose, up to $299/mo at higher doses. brand pathway $99/mo + pharmacy cost.), while Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.).
Do ShedRx and Sesame Care accept insurance?
ShedRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does ShedRx offer vs Sesame Care?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel ShedRx or Sesame Care at any time?
ShedRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are ShedRx and Sesame Care available in my state?
ShedRx is available in all 50 states. Sesame Care is available in all 50 states.