Sesame Care vs MangoRx: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Sesame Care and MangoRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend MangoRx

Between these two providers, MangoRx is our pick for most users. It offers a higher overall rating (7.5 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.

MangoRx scores 7.5/10 in our independent evaluation at $195/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
Sesame Care
$225
MangoRx
$195
Rating
Sesame Care
7.2 / 10
MangoRx
7.5 / 10
Medication Type
Sesame Care
Brand & Compounded
MangoRx
Compounded Only
Insurance Accepted
Sesame Care
Yes
MangoRx
No
States Available
Sesame Care
All 50 states
MangoRx
45 states
Consultation Fee
Sesame Care
$25-75
MangoRx
Free
Shipping
Sesame Care
Paid
MangoRx
Free Shipping
Cancel Anytime
Sesame Care
Yes
MangoRx
Yes
Medical Support
Sesame Care
Licensed physicians, per-visit model
MangoRx
Licensed U.S. physicians, ongoing support

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

Sesame Care: Detailed Look

Sesame Care

Affordable telehealth marketplace connecting patients with doctors from $25

7.2/10
Good

Pros

  • Lowest consultation cost — visits from just $25
  • Prescribes brand-name FDA-approved medications
  • Transparent per-visit pricing with no subscriptions
  • Wide network of licensed physicians across all 50 states

Cons

  • Medication cost is separate and not included in visit fee
  • No compounded options — brand-name only (higher drug cost)
Best For

Users with insurance who want cheap doctor visits — medication costs are separate and not included

MangoRx: Detailed Look

MangoRx

Telehealth platform for weight loss, men's health, and wellness

7.5/10
Good

Pros

  • Multi-service platform — weight loss, ED, hair loss, skincare
  • Licensed U.S. physicians prescribe all medications
  • Free shipping on all orders
  • Simple online intake with no appointment needed

Cons

  • Pricing details require completing intake form
  • Compounded medications only — no brand-name options
Best For

Users who want a multi-service telehealth platform covering weight loss and men's health

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with MangoRx at $195/month. Estimated starting price for GLP-1 program.

You want the highest-rated program

MangoRx has the edge with a 7.5 rating.

You have insurance coverage

Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.

You want affordable compounded options

MangoRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Sesame Care offers licensed physicians, per-visit model, while MangoRx provides licensed u.s. physicians, ongoing support.

You are willing to invest more for premium care

Sesame Care at $225/month may offer features that justify the premium.

Sesame Care

Starting at $225/mo · Good

Visit Sesame Care

MangoRx

Starting at $195/mo · Good

Visit MangoRx

Frequently Asked Questions

Is Sesame Care better than MangoRx?

Sesame Care has a 7.2 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included, while MangoRx is best for users who want a multi-service telehealth platform covering weight loss and men's health.

How much does Sesame Care cost compared to MangoRx?

Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.), while MangoRx starts at $195/month (estimated starting price for glp-1 program).

Do Sesame Care and MangoRx accept insurance?

Sesame Care accepts insurance. MangoRx does not accept insurance.

Which GLP-1 medications does Sesame Care offer vs MangoRx?

Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus. MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel Sesame Care or MangoRx at any time?

Sesame Care allows cancel anytime. MangoRx also allows cancel anytime.

Are Sesame Care and MangoRx available in my state?

Sesame Care is available in all 50 states. MangoRx is available in 45 states.