Enhance MD vs AgelessRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and AgelessRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.1). That said, AgelessRx may be the better fit if you are looking for longevity-minded users who want glp-1 alongside anti-aging treatments.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while AgelessRx scores 6.1/10 at $139/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | AgelessRx |
|---|---|---|
| Monthly Price | $249 | $139 |
| Rating | 8.3 / 10 | 6.1 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed providers, ongoing clinical support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
AgelessRx: Detailed Look
AgelessRx
Longevity-focused telehealth with compounded GLP-1s and oral drops
Pros
- Longevity platform — also offers NAD+, rapamycin, metformin
- Oral GLP-1 drops available for needle-free option
- Free consultations with no separate provider fees
- Available in all 50 states with HSA/FSA accepted
Cons
- Cold-shipped injectables may not be available in Alaska/Hawaii
- Compounded medications are not FDA-reviewed for safety
Longevity-minded users who want GLP-1 alongside anti-aging treatments
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with AgelessRx at $139/month. $139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Enhance MD offers board-certified physicians, while AgelessRx provides licensed providers, ongoing clinical support.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than AgelessRx?
Enhance MD has a 8.3 rating while AgelessRx has a 6.1 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while AgelessRx is best for longevity-minded users who want glp-1 alongside anti-aging treatments.
How much does Enhance MD cost compared to AgelessRx?
Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%), while AgelessRx starts at $139/month ($139/mo semaglutide, $249/mo tirzepatide, $149/mo liraglutide).
Do Enhance MD and AgelessRx accept insurance?
Enhance MD does not accept insurance. AgelessRx does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs AgelessRx?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. AgelessRx offers Compounded Semaglutide, Compounded Tirzepatide, Compounded Liraglutide, Oral GLP-1 Drops, Wegovy, Zepbound.
Can I cancel Enhance MD or AgelessRx at any time?
Enhance MD allows cancel anytime. AgelessRx also allows cancel anytime.
Are Enhance MD and AgelessRx available in my state?
Enhance MD is available in all 50 states. AgelessRx is available in all 50 states.