Willow vs Enhance MD: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Willow and Enhance MD to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.9). That said, Willow may be the better fit if you are looking for users who want a balance of quality care and reasonable pricing.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Willow scores 6.9/10 at $160/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Willow | Enhance MD |
|---|---|---|
| Monthly Price | $160 | $249 |
| Rating | 6.9 / 10 | 8.3 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, ongoing check-ins | Board-certified physicians |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Personalized treatment plans tailored to your health profile
- Licensed physicians in all 50 states
- Both brand-name and compounded options available
- Free shipping with cancel-anytime flexibility
Cons
- Higher starting price than some compounded-only options
- Newer platform — fewer long-term patient reviews available
Users who want a balance of quality care and reasonable pricing
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Willow at $160/month. Starting price, varies by medication.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Willow offers licensed physicians, ongoing check-ins, while Enhance MD provides board-certified physicians.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Willow better than Enhance MD?
Willow has a 6.9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Willow is best for users who want a balance of quality care and reasonable pricing, while Enhance MD is best for budget-conscious users interested in combination therapies.
How much does Willow cost compared to Enhance MD?
Willow starts at $160/month (starting price, varies by medication), while Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%).
Do Willow and Enhance MD accept insurance?
Willow does not accept insurance. Enhance MD does not accept insurance.
Which GLP-1 medications does Willow offer vs Enhance MD?
Willow offers Semaglutide, Tirzepatide. Enhance MD offers Semaglutide, Tirzepatide, NAD+.
Can I cancel Willow or Enhance MD at any time?
Willow allows cancel anytime. Enhance MD also allows cancel anytime.
Are Willow and Enhance MD available in my state?
Willow is available in all 50 states. Enhance MD is available in all 50 states.